Douglas Adkins Selected Research

sitravatinib

10/2022

First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors.

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Douglas Adkins Research Topics

Disease

26	Squamous Cell Carcinoma of Head and Neck 05/2022 - 01/2013
17	Neoplasms (Cancer) 10/2022 - 02/2013
7	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021 - 03/2013
4	Neutropenia 01/2019 - 01/2011
4	Sarcoma (Soft Tissue Sarcoma) 07/2016 - 01/2011
3	Disease Progression 01/2021 - 01/2019
3	Oropharyngeal Neoplasms 05/2019 - 01/2017
3	Stomatitis 01/2018 - 12/2016
3	Graft vs Host Disease (Graft-Versus-Host Disease) 07/2009 - 01/2006
2	Carcinoma (Carcinomatosis) 03/2022 - 01/2018
2	Fatigue 01/2020 - 01/2018
2	Lymphopenia (Lymphocytopenia) 05/2019 - 11/2018
2	Squamous Cell Neoplasms (Squamous Cell Cancer) 11/2018 - 04/2015
2	Vomiting 01/2018 - 07/2016
2	Infections 01/2018 - 09/2017
2	Nausea 01/2018 - 07/2016
2	Febrile Neutropenia 07/2016 - 03/2013
2	Mucositis 07/2016 - 06/2003
1	medullary Thyroid cancer 01/2021
1	Extranodal Extension 01/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021
1	Thyroid Neoplasms (Thyroid Cancer) 01/2021
1	Leukopenia 01/2020
1	Nasopharyngeal Carcinoma 01/2018
1	Paresthesia (Dysesthesia) 01/2018
1	Proteinuria 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 05/2017
1	Inflammation (Inflammations) 12/2016
1	Bacterial Infections (Bacterial Infection) 12/2016
1	Hypoxia (Hypoxemia) 01/2011

Drug/Important Bio-Agent (IBA)

15	Cetuximab (Erbitux)FDA Link 03/2021 - 01/2013
7	Cisplatin (Platino)FDA LinkGeneric 03/2021 - 01/2013
6	130-nm albumin-bound paclitaxelIBA 03/2021 - 02/2013
5	Docetaxel (Taxotere)FDA Link 02/2017 - 03/2013
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2014
4	PlatinumIBA 01/2021 - 01/2016
3	palbociclibIBA 01/2021 - 01/2016
3	temsirolimus FDA Link 01/2020 - 08/2011
3	Fluorouracil (Carac)FDA LinkGeneric 10/2016 - 02/2013
3	Monoclonal AntibodiesIBA 10/2016 - 09/2014
2	Phosphotransferases (Kinase)IBA 10/2022 - 04/2015
2	pembrolizumabIBA 03/2022 - 01/2021
2	Albumin-Bound Paclitaxel FDA Link 01/2021 - 02/2017
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2021
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 02/2017
2	vandetanib (ZD6474)IBA 01/2021 - 08/2013
2	Cyclin-Dependent Kinase 4IBA 01/2019 - 01/2016
2	Cyclin D1IBA 01/2019 - 01/2016
2	dusquetideIBA 09/2017 - 12/2016
2	Panitumumab (Vectibix)FDA Link 10/2016 - 01/2016
2	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2016 - 01/2011
2	thiamine triphosphorate (TTP)IBA 01/2016 - 12/2014
2	TOR Serine-Threonine KinasesIBA 04/2015 - 08/2011
1	sitravatinibIBA 10/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2022
1	c-Mer Tyrosine KinaseIBA 10/2022
1	Messenger RNA (mRNA)IBA 05/2022
1	Biological ProductsIBA 05/2022
1	acalabrutinibIBA 03/2022
1	Agammaglobulinaemia Tyrosine KinaseIBA 03/2022
1	RNA (Ribonucleic Acid)IBA 03/2021
1	Carboplatin (JM8)FDA LinkGeneric 01/2021
1	cabozantinibIBA 01/2021
1	pralsetinibIBA 01/2021
1	AlbuminsIBA 01/2021
1	ElectrolytesIBA 01/2020
1	avasopasem manganeseIBA 01/2018
1	pazopanib FDA Link 01/2018
1	Superoxide DismutaseIBA 01/2018
1	SuspensionsIBA 01/2018
1	Angiogenesis InhibitorsIBA 01/2018
1	AntigensIBA 09/2017
1	entinostat (MS 275)IBA 05/2017
1	Taxoids (Taxanes)IBA 02/2017
1	cremophorIBA 02/2017
1	taxaneIBA 02/2017
1	ErbB Receptors (EGF Receptor)IBA 10/2016
1	AnthracyclinesIBA 07/2016
1	Growth Factor ReceptorsIBA 07/2016
1	olaratumabIBA 07/2016
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2016
1	Retinoblastoma ProteinIBA 01/2016
1	PX-866IBA 04/2015
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 04/2015
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2015
1	AntibodiesIBA 10/2014
1	Neuregulin-1 (Neuregulin 1)IBA 10/2014
1	cixutumumabIBA 04/2013
1	ProdrugsIBA 01/2011
1	TH 302IBA 01/2011

Therapy/Procedure

15	Therapeutics 03/2022 - 09/2014
6	Induction Chemotherapy 03/2021 - 02/2013
5	Drug Therapy (Chemotherapy) 01/2021 - 04/2013
5	Radiotherapy 05/2019 - 01/2013
3	Chemoradiotherapy 03/2021 - 03/2013
3	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 10/2007 - 03/2003
2	Immunotherapy 01/2021 - 01/2017
2	Transplantation 06/2003 - 03/2003
1	Neck Dissection (Radical Neck Dissection) 10/2019
1	Aftercare (After-Treatment) 05/2019